I obtained a bachelor's degree in biochemistry from the university of Oran (Algeria) in 2004. I then moved to France for a master1 (Limoges) and then a master2 and a PhD carried out in the laboratory of Alain Vincent at the Center for Developmental Biology (2008-2012, Toulouse). From 2013 to 2019 I took a postdoctoral position in the laboratory of Sarah Bray at University of Cambridge (United Kingdom), supported by EMBO long term fellowship. In 2020, I obtained an ATIP-Avenir funding and, the following year, I created the “Muscle Development and Repair” team at the Institute of Genetics and Development of Rennes (IGDR, Rennes). I am interested in understanding the molecular and cellular mechanisms that regulate development and tumorigenesis.
Outside the lab I can most likely be found on a Rowing boat !
Research assistant/Lab manager (UR1)
After a master's degree in Cellular and Molecular Life Sciences, I did my PhD at the Institut de Génétique et Développement de Rennes (IGDR) on the topics of microtubule dynamics and mitotic spindle assembly. I was then awarded an EMBO Long Term Fellowship to study the establishment of centrosome asymmetry in Drosophila neuroblasts, a feature common to many stem cells. I did this work during my first postdoctoral training at the Biozentrum (Basel, Switzerland). I then returned to the IGDR to study the molecular coupling of asymmetric cell division and mitotic progression of Drosophila neuroblasts, two processes required to maintain tissue homeostasis. I am now focusing on the early mechanisms of satellite cell activation for muscle maintenance and repair. I use the Drosophila flight muscleas a model to decipher the role of the chromatin remodeling enzyme Lsd1 in the context of muscle regeneration.
PhD student (AFM Fellow)
I started my university education at the Biotechnology Institute in Tunisia, then I moved to the University of Toulouse, where I obtained a master degree Developmental biology. I’m currently in my second-year of PhD, and my research focuses on the genes and mechanisms that regulate adult muscle stem cells activation during muscle regeneration and repair.
After completing my master's degree of Molecular and Cellular Biology at the University of Rennes 1, I started my thesis in the Muscle Development and Repair team in October 2022.
My project consists to study Notch signaling pathway dynamic at the different stages of the differentiation process, from stem cell to differentiated muscle cell.
I did my undergrad degree in Earth and Life Sciences in the University of New Caledonia, then I moved to France for a Master degree in Molecular and Cellular Biology (University of Rennes). I am now completing the second year of my master's degree with an internship in the Muscle Development and Repair team at IGDR. My project consists to study the transcription dynamic of the Notch signalling pathway during the activation and differentiation of muscle stem cells in drosophila.
Aïssatou Dieng (2022) Master 2 student (Paris Sorbonne)
Manon Jacquet (2022) Master 1 student (Université de Rennes)
Elodie Marchal (2022) Undergrad student (L2) (Université de Rennes)